Vardenafil

CFTR activator

Phase of research

FDA-/EMA-approved for Other Purpose

How it helps

Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

N/A

Dietary sources

N/A

Structure not available

C23H32N6O4S

Drug-Mutation Relation

results for D1152H / F508del
See all data on Vardenafil

Treats

Mutation Link Tested on Impact factor Notes
F508del Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice mice 5.90 More effective than sildenafil but less effective than tadalafil.
F508del Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. mice 9.79

Does not treat

Mutation Link Tested on Impact factor Notes