Vardenafil

CFTR activator

Phase of research

FDA-/EMA-approved for Other Purpose

How it helps

Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

N/A

Dietary sources

N/A

Structure not available

C23H32N6O4S

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
2 7.85
Link Tested on Impact factor Notes
Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice mice 5.90 More effective than sildenafil but less effective than tadalafil.
Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. mice 9.79

Does not treat

Mutation Number of sources Average impact factor