PEMA

CFTR corrector and potentiator

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

N/A

Synonyms

4-propyl-6-ethyl-4′-methylangelicin

Marketed as

N/A

Dietary sources

N/A

Structure image not available

N/A

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
1 3.85
Link Tested on Impact factor Notes
Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators human cell cultures 3.85 Less effective than TMA or lumacaftor.
G551D
1 3.85
Link Tested on Impact factor Notes
Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators human cell cultures 3.85 Comparable to genistein.

Does not treat

Mutation Number of sources Average impact factor