Paromomycin

Aminoglycoside capable of translational readthrough

Phase of research

FDA-/EMA-approved for Other Purpose

How it helps

Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

N/A

Dietary sources

N/A

Structure not available

C23H45N5O14

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
G542X
1 5.21
Link Tested on Impact factor Notes
Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. in vitro 5.21 Less effective than NB54 or gentamycin, more effective than NB30. More toxic than NB54 or NB30.
W1282X
1 5.21
Link Tested on Impact factor Notes
Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. in vitro 5.21 Less effective than NB54 or gentamycin, more effective than NB30. More toxic than NB54 or NB30.

Does not treat

Mutation Number of sources Average impact factor