NCI407882

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

N/A

Dietary sources

N/A

Structure not available

C14H16O4P2

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
1 8.25
Link Tested on Impact factor Notes
Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain. human cell cultures 8.25 More effective than Corr-4a and comparable to lumacaftor. Better with NCI118208.

Does not treat

Mutation Number of sources Average impact factor