NB54

Aminoglycoside capable of translational readthrough

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

N/A

Dietary sources

N/A

Structure image not available

N/A

Drug-Mutation Relation

results for D1152H / F508del
See all data on NB54

Treats

Mutation Link Tested on Impact factor Notes

Does not treat

Mutation Link Tested on Impact factor Notes
F508del/F508del Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54. human cell cultures 4.67