Miglustat 

CFTR corrector

Phase of research

FDA-/EMA-approved for Other Purpose

How it helps

Restore CFTR Function

General information

N/A

Synonyms

n-butyldeoxynojyrimicin, NB-DNJ

Marketed as

Dietary sources

N/A

Structure not available

C10H21NO4

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
2 7.50
Link Tested on Impact factor Notes
Airway Delivery of Low-Dose Miglustat Normalizes Nasal Potential Difference in F508del Cystic Fibrosis Mice mice 10.69
Proteasome-Dependent Pharmacological Rescue of Cystic Fibrosis Transmembrane Conductance Regulator Revealed by Mutation of Glycine 622 human cell cultures 4.31
G622D
1 4.31
Link Tested on Impact factor Notes
Proteasome-Dependent Pharmacological Rescue of Cystic Fibrosis Transmembrane Conductance Regulator Revealed by Mutation of Glycine 622 human cell cultures 4.31

Does not treat

Mutation Number of sources Average impact factor