Curcumin
CFTR potentiator
General information
Curcumin is a bright yellow substance produced by Curcuma longa plants. It exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing and antimicrobial activities. While it is not approved as a medical product, it is sold as an herbal supplement, cosmetics ingredient, and food coloring and flavoring. In relation to cystic fibrosis, our AIM tool found the data that curcumin can help potentiate G551D-CFTR and W1282X-CFTR channels and restore the expression of F508del-CFTR in the plasma membrane.
Curcumin on PubChem
Curcumin on DrugBank
Curcumin on Wikipedia
Synonyms
N/A
Marketed as
N/A
Dietary sources
turmeric
C21H20O6
Drug-Mutation Relation
results for D1152H / F508del
See all data on CurcuminTreats
| Mutation | Link | Tested on | Impact factor | Notes |
|---|---|---|---|---|
| F508del | Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines. | human cell cultures | 4.49 |
Does not treat
| Mutation | Link | Tested on | Impact factor | Notes |
|---|