Caveolin 2

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

Caveolin 2 is a protein naturally present in our cells, not available as a human pharmaceutical. It is present in the plasma membrane and involved in essential cellular functions, such as signaling, growth, and death of the cell. It is also a potential tumor suppressor. In relation to cystic fibrosis, our AIM tool found the data that caveolin 2 can correct F508del-CFTR by enhancing its maturation and cell surface expression.

Caveolin 2 on Wikipedia

Synonyms

Cav2

Marketed as

N/A

Dietary sources

N/A

Structure image not available

N/A

Drug-Mutation Relation

results for D1152H / F508del

See all data on Caveolin 2

Treats

Mutation	Link	Tested on	Impact factor	Notes
F508del	High-content Functional Screen to Identify Proteins that Correct F508del-CFTR Function*S⃞	human cell cultures	7.52	Better than Corr-4a.

Does not treat

Mutation	Link	Tested on	Impact factor	Notes