Caveolin 2

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

Caveolin 2 is a protein naturally present in our cells, not available as a human pharmaceutical. It is present in the plasma membrane and involved in essential cellular functions, such as signaling, growth, and death of the cell. It is also a potential tumor suppressor. In relation to cystic fibrosis, our AIM tool found the data that caveolin 2 can correct F508del-CFTR by enhancing its maturation and cell surface expression. 

Caveolin 2 on Wikipedia

Synonyms

Cav2

Marketed as

N/A

Dietary sources

N/A

Structure image not available

N/A

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
1 7.52
Link Tested on Impact factor Notes
High-content Functional Screen to Identify Proteins that Correct F508del-CFTR Function*S⃞ human cell cultures 7.52 Better than Corr-4a.

Does not treat

Mutation Number of sources Average impact factor