AP2M1

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function


General information

AP2M1 is a protein naturally present in our cells. It is a substance used in experimental studies and not yet available as a human pharmaceutical.  In relation to cystic fibrosis, out AIM tool found the data that AP2M1 helps rescue the trafficking of F508del-CFTR and enhances its cell surface expression.

AP2M1 on Wikipedia


Synonyms

Adapter protein 2, AP2


Marketed as

N/A


Dietary sources

N/A

Structure image not available

N/A


Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
1 7.52
Link Tested on Impact factor Notes
High-content Functional Screen to Identify Proteins that Correct F508del-CFTR Function*S⃞ human cell cultures 7.52

Does not treat

Mutation Number of sources Average impact factor