ALLO

CFTR corrector and potentiator

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

ALLO is a substance used in experimental studies and not yet available as a human pharmaceutical. In relation to cystic fibrosis, our AIM tool found the data that ALLO is effective in both correcting F508del-CFTR and potentiating CFTR-dependent chloride transport.

ALLO on PubChem

Synonyms

4,7,4′-trimethylallopsoralen

Marketed as

N/A

Dietary sources

N/A

Structure not available

C14H12O3

Drug-Mutation Relation

Treats

Mutation Number of sources Average impact factor
F508del
1 3.85
Link Tested on Impact factor Notes
Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators human cell cultures 3.85 Less effective than TMA or lumacaftor.
G551D
1 3.85
Link Tested on Impact factor Notes
Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators human cell cultures 3.85 Comparable to genistein.

Does not treat

Mutation Number of sources Average impact factor