1-EBIO

CFTR potentiator

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

1-EBIO is an experimental substance used in studies and not yet available as a human pharmaceutical. Based on its characteristics as a calcium channel agonist, it has the potential to combat cardiac failure and endocrinological disorders.  In relation to cystic fibrosis, our AIM tool found the data that 1-EBIO can help potentiate mutant CFTR channels that have a residual function.

1-EBIO on PubChem

Synonyms

1-ethyl-2-benzimidazolone

Marketed as

N/A

Dietary sources

N/A

Structure not available

C9H10N2O

Drug-Mutation Relation

results for D1152H / F508del
See all data on 1-EBIO

Treats

Mutation Link Tested on Impact factor Notes

Does not treat

Mutation Link Tested on Impact factor Notes
F508del/F508del The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies from Cystic Fibrosis Patients human cell cultures 4.09