Filter the drugs by the phase of research, how they help and the responsive mutations.
Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene. Browse the
database of
drugs treating specific mutations compiled by the AIM tool.
| Drug | Marketed as | Description | Phase of research | How it helps |
|---|---|---|---|---|
| Osthole | Coumarin compound from Chinese medicinal herbs, CFTR activator |
Accessible Dietary Supplement | Restore CFTR Function | |
| Ouabain | plant-derived toxic substrance, CFTR corrector |
Pre-clinical | Restore CFTR Function | |
| PAP | CFTR corrector |
Pre-clinical | Restore CFTR Function | |
| PEMA | CFTR corrector and potentiator |
Pre-clinical | Restore CFTR Function | |
| PFDN2 | CFTR corrector |
Pre-clinical | Restore CFTR Function | |
| POL6014 | Neutrophil elastase inhibitor |
Phase One Clinical Trial | Anti-Inflammatory | |
| Pancrelipase enzyme | Pertzye® | Digestive enzymes |
FDA-approved for Cystic Fibrosis | Nutritional-GI-Other |
| Pancrelipase enzyme | Zenpep® | Digestive enzymes |
FDA-approved for Cystic Fibrosis | Nutritional-GI-Other |
| Pancrelipase enzyme | Pancreaze® | Digestive enzymes |
FDA-approved for Cystic Fibrosis | Nutritional-GI-Other |
| Pancrelipase enzyme | Creon® | Digestive enzymes |
FDA-approved for Cystic Fibrosis | Nutritional-GI-Other |
