Filter the drugs by the phase of research, how they help and the responsive mutations.

Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene. Browse the database of drugs treating specific mutations compiled by the AIM tool.
Drug Marketed as Description Phase of research How it helps
NB30 

Aminoglycoside capable of translational readthrough

Pre-clinical Restore CFTR Function
NB54

Aminoglycoside capable of translational readthrough

Pre-clinical Restore CFTR Function
NCI118208

CFTR corrector

Pre-clinical Restore CFTR Function
NCI130813

CFTR corrector

Pre-clinical Restore CFTR Function
NCI407882

CFTR corrector

Pre-clinical Restore CFTR Function
NCI73100

CFTR corrector

Pre-clinical Restore CFTR Function
NS004

Enhances CFTR activity

Pre-clinical Restore CFTR Function
Nitric oxide

Gas with antimicrobial properties

Phase Two Clinical Trial Anti-Infective
OligoG

Decreases the thickness of mucus in the lungs

Phase Two Clinical Trial Mucociliary Clearance
Omalizumab  Xolair®

Treats CF-related allergic bronchopulmonary aspergillosis

FDA-/EMA-approved for Other Purpose Nutritional-GI-Other