Tobramycin

Aminoglycoside antibiotic capable of translational readthrough

Phase of research

FDA-/EMA-approved for Cystic Fibrosis

How it helps

Anti-Infective,Restore CFTR Function

General information

N/A

Synonyms

N/A

Marketed as

Dietary sources

N/A

Structure not available

C18H37N5O9

Drug-Mutation Relation

results for R352Q / G542X
See all data on Tobramycin

Treats

Mutation Link Tested on Impact factor Notes
G542X Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene. mice 3.30
General effect Arikace compared to TOBI® in people with CF with chronic Pseudomonas aeruginosa infections (Insmed TR02-108) humans N/A More effective than Amikacin.
General effect Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial. humans 3.19 Tobramycin inhalation powder is more convenient than tobramycin inhalation solution.

Does not treat

Mutation Link Tested on Impact factor Notes