HspA4

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

HspA4 is a protein naturally present in our cells. In the cell, it acts as a chaperone, which helps proteins to fold properly. It is not available as a human pharmaceutical. In relation to cystic fibrosis, our AIM tool found the data that HspA4 can help rescue F508del-CFTR by enhancing its maturation and expression on the cell surface.

HspA4 on Wikipedia

Synonyms

Heat shock protein A4

Marketed as

N/A

Dietary sources

N/A

Structure image not available

N/A

Drug-Mutation Relation

results for D1152H / F508del

See all data on HspA4

Treats

Mutation	Link	Tested on	Impact factor	Notes
F508del	High-content Functional Screen to Identify Proteins that Correct F508del-CFTR Function*S⃞	human cell cultures	7.52

Does not treat

Mutation	Link	Tested on	Impact factor	Notes