CF(cor)-325

CFTR corrector

Phase of research

Pre-clinical

How it helps

Restore CFTR Function

General information

CF(cor)-325 is an experimental substance used in studies and not yet available as a human pharmaceutical. In relation to cystic fibrosis, our AIM tool found the data that CF(cor)-325 can rescue misprocessed CFTR mutants, including F508del, R258G, S945L, and H949Y.

CF(cor)-325 on PubChem

Synonyms

VRT-325, 4-cyclohexyloxy-2-{1-[4-(4-methoxy-benzenesulfonyl)piperazin-1-yl]ethyl}quinazoline

Marketed as

N/A

Dietary sources

N/A

C₂₇H₃₄N₄O₄S

Drug-Mutation Relation

results for 120del23 / R258G

See all data on CF(cor)-325

Treats

Mutation	Link	Tested on	Impact factor	Notes
R258G	Rescue of DeltaF508 and other misprocessed CFTR mutants by a novel quinazoline compound.	human cell cultures	N/A

Does not treat

Mutation	Link	Tested on	Impact factor	Notes