Filter the drugs by the phase of research, how they help and the responsive mutations.

Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene. Browse the database of drugs treating specific mutations compiled by the AIM tool.
Drug Marketed as Description Phase of research How it helps
Tezacaftor Symdeko® (ivacaftor/tezacaftor), Symkevi® (ivacaftor/tezacaftor), Trikafta™(elexacaftor/tezacaftor/ivacaftor)

CFTR corrector

FDA-/EMA-approved for Cystic Fibrosis Restore CFTR Function
Tobramycin TOBI® Podhaler™

Aminoglycoside antibiotic capable of translational readthrough

FDA-/EMA-approved for Cystic Fibrosis Anti-Infective,Restore CFTR Function

CFTR activator

FDA-/EMA-approved for Other Purpose Restore CFTR Function