Filter the drugs by the phase of research, how they help and the responsive mutations.
Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene. Browse the
database of
drugs treating specific mutations compiled by the AIM tool.
Drug | Marketed as | Description | Phase of research | How it helps |
---|---|---|---|---|
Apigenin | Flavonoid activator of CFTR |
Accessible Dietary Supplement | Restore CFTR Function | |
AquADEKs® | AquADEKs® | Antioxidant-enriched multivitamin supplement |
Accessible Dietary Supplement | Nutritional-GI-Other |
Ataluren | Translarna™ | Suppresses premature stop mutation |
EMA-approved for Other Purpose | Restore CFTR Function |
Azithromycin | Zithromax® | Antibiotic with anti-inflammatory properties |
FDA-approved for Cystic Fibrosis | Anti-Infective |
Aztreonam | Cayston® | Antibiotic |
FDA-/EMA-approved for Cystic Fibrosis | Anti-Infective |
Bortezomib | Velcade® | Proteasome inhibitor preventing premature CFTR breakdown |
FDA-/EMA-approved for Other Purpose | Restore CFTR Function |
Buserelin | Gonadotropin-Releasing Hormone analog restoring CFTR channel function |
EMA-approved for Other Purpose | Restore CFTR Function | |
C18 | Small molecule CFTR corrector |
Pre-clinical | Restore CFTR Function | |
C3 | Small molecule CFTR corrector |
Pre-clinical | Restore CFTR Function | |
C4 | Small molecule CFTR corrector |
Pre-clinical | Restore CFTR Function |